Fisurectomy and anoplasty with botulinum toxin injection in patients with chronic anal posterior fissure with hypertonia: a long-term evaluation

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Sustained internal sphincter hypertonia in patients with chronic anal fissure.

PURPOSE This study was designed to determine whether functional variations of internal sphincter activity occur in order to differentiate between patients with anal fissures from those with hemorrhoids. METHODS Thirty patients with chronic anal fissure (median age, 28 years; 12 females), 22 patients with hemorrhoids (median age, 37 years; 7 females), and 33 control volunteers (median age, 48....

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Botulinum toxin for chronic anal fissure.

Botulinum toxin can chemically denervate striated muscle. Botulinum toxin A (15 U) was used to treat ten patients with chronic anal fissure by injection in the internal sphincter. In seven patients, the lesion healed at 2 months after treatment; one relapsed at 3 months. In one patient the lesion healed at 1 month, but partly relapsed a month later. Mild faecal incontinence lasting for 1 day wa...

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Botulinum toxin treatment for anal fissure.

OBJECTIVES To evaluate the effectiveness of Botulinum toxin injection in the treatment of anal fissure. METHODS 38 patients (22 males, 16 females; mean age (SD) of 33.3 (8.3) years) who have presented to Surgical Outpatient Clinic at Al Ain Hospital, United Arab Emirates, with anal fissure in the period between June 2000 and September 2001 and treated with Botulinum toxin injection were retro...

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ژورنال

عنوان ژورنال: Updates in Surgery

سال: 2020

ISSN: 2038-131X,2038-3312

DOI: 10.1007/s13304-020-00846-y